Bioinformatics experts see cloud-based computing and data storage as the most effective way to manage and use rapidly growing biomedical datasets. (Photo by Elena Zhukova)

Bioinformatics leaders partner to build platform for NIH Data Commons

UC Santa Cruz Genomics Institute, University of Chicago, and the Broad Institute will create the Commons Alliance Platform with funding from the National Institutes of Health November 06, 2017 By Tim Stephens The life sciences are in the midst of a data revolution. Technologies such as …

A Data Biosphere for Biomedical Research

By Benedict Paten We, the authors listed below, are privileged to be part of the growing global community bringing data and life science together. Our groups have been working together in overlapping combinations during the past two years to drive the creation of data commons …

This prototype visualization of a genomic variation graph zooms in on portions of the NOTCH2 gene, an important gene for development. The colored bands represent 5 different variants of the gene, with rectangular shapes representing nodes (shared DNA sequences) and the colored ribbons between nodes representing paths/edges (not sequences). In the top panel, introns are shaded out (at right and left) while the solid colors represent exons 4 and 5. The exons are shown in increasingly greater detail in the bottom two panels. The visualization tool can also provide an intuitive graphical view of inversions, as shown in the green and red loops in the simulated example to the right. Images courtesy of Wolfgang Beyer, software developer for the Computational Genomics Laboratory at the University of California, Santa Cruz.

Visualizing Human Genome Variation

A comprehensive, genomic variation graph offers an intuitive view of how human genomes vary Biomedical Computation Review | By Katharine Miller Humans share 99.5 percent of their DNA sequence, but that still leaves plenty of variation to go around. To get a handle on which …

David Haussler Team Pic

2017 Assembly: Mapping Open Research Ecosystems

April 20 – 22, 2017 – Seattle, WA Hosted by Sage Bionetworks Sage Assmbly invited speaker David Haussler, UC Santa Cruz Genomics Institute’s Scientific Director, addresses the plenary session with his talk, “Evolution of Concepts in Open Ecosystems – Part 2.” Watch the video here.

[Tues. May 16th, 2017] Genomics Institute Seminar: Siddartha Jain

Siddartha Jain Computer Science Department, Carnegie Mellon University Inferring temporal signaling pathways and regulatory networks, and classifying cell types from high-throughput data Tuesday, May 16, 2017 11:00 AM – 12:00 PM 599 Engineering 2 Abstract Cells need to be able to sustain themselves, divide, and …

Children’s Hospitals Incorporating Genomic Testing

Panelists offer details on research programs using genetic information to diagnose and treat tragic childhood diseases. By Steve Sternberg | Senior Writer Nov. 4, 2016, at 2:47 p.m. Read the full article here  

MinION sequencer
“Oxford Nanopore has excited the world with the promise of a technology that can be truly disruptive,” says David Buck of Oxford University.

Mini DNA sequencer tests true

By Mary Todd Bergman:
Public access to Oxford Nanopore’s MinION™ USB-attached miniature sensing device enabled an international consortium to evaluate the technology and provide a standard protocol for its use; Preliminary analysis of data generated in five very different laboratories indicates the performance and accuracy of the device is consistently good; Data are freely available for re-analysis and innovation in the Nanopore analysis channel on F1000Research.